What Is Nerolidol Terpene and How Does It Work?
What Is Nerolidol Terpene and How Does It Work?
As medical cannabis becomes more widely prescribed in the UK, patients are starting to learn not just about cannabinoids such as THC and CBD, but also about terpenes.
Terpenes are the aromatic compounds that give cannabis its distinctive smell and may also contribute therapeutic effects. One terpene that has gained attention in recent years is nerolidol—a floral, woody-scented terpene with a range of potential health benefits.
In this guide, we’ll explore what nerolidol is, its aroma profile, where else it can be found, and what the research says about its potential effects for patients.
Contents
What is Nerolidol?
Nerolidol—sometimes referred to as trans-nerolidol—is a terpene found in cannabis and many other aromatic plants, including jasmine, lemongrass, ginger, and tea tree. Like other terpenes, nerolidol plays a role in the entourage effect, where cannabinoids and terpenes work together to enhance the therapeutic potential of cannabis.
While nerolidol is considered a secondary terpene (less dominant compared to limonene or myrcene), it still has an important influence on the overall experience of certain cannabis strains.
What Does Nerolidol Smell Like?
Patients who encounter nerolidol-rich strains often describe its scent as floral, woody, and slightly fruity. More specifically, nerolidol carries notes of:
- Fresh bark
- Citrus and melon
- Hints of rose and apple
- Subtle lemongrass tones
Thanks to this distinct aroma, nerolidol is not only found in cannabis but is also widely used in perfumes, lotions, cleansers, detergents, and even food flavourings.
Where Else Can You Find Nerolidol?
Nerolidol occurs naturally in a variety of plants beyond cannabis, including:
- Jasmine
- Lavender
- Lemongrass
- Ginger
- Tea tree
- Roses
Its pleasant scent and antimicrobial properties mean it has long been used in essential oils, skincare, and as a natural insect repellent.
Nerolidol Terpene Effects
Research into nerolidol terpene effects is still developing, but early findings suggest it may offer several therapeutic benefits:
- Sedative and calming effects – potentially useful for patients managing insomnia or stress.
- Anti-anxiety properties – supporting relaxation without heavy psychoactive effects.
- Antioxidant and anti-inflammatory activity – potentially relevant to conditions such as Parkinson’s Disease.
- Antimicrobial and antifungal properties – showing activity against certain bacteria and fungi.
- Pain-relieving potential – may contribute to analgesic effects.
Additionally, nerolidol may enhance skin permeability, improving the delivery of certain medicines or therapeutic compounds through topical applications.
Which Cannabis Strains Contain Nerolidol?
Not every strain is high in nerolidol, but some commonly noted strains include:
- Jack Herer – a well-balanced hybrid with uplifting yet calming effects.
- Skywalker OG – often described as deeply relaxing and body-focused.
- Island Sweet Skunk – a strain with both fruity aromas and grounding effects.
Patients interested in nerolidol-rich strains should speak with their prescribing clinician and review lab-tested products to ensure they select strains with terpene profiles that meet their needs.
Why Do Terpenes Like Nerolidol Matter?
For medical cannabis patients in the UK, terpenes are more than just aroma. They may:
- Contribute to therapeutic effects
- Influence how cannabinoids like THC and CBD work in the body
- Help patients find strains better tailored to their health needs
Understanding terpenes such as nerolidol can empower patients to make more informed choices when it comes to treatment.
Final Thoughts: Nerolidol and Medical Cannabis in the UK
Nerolidol is an intriguing terpene with a calming, floral scent and promising therapeutic potential. From sedative effects that may help with sleep to antimicrobial and antioxidant properties, early research highlights nerolidol as a valuable component of certain cannabis strains.
At CB1 Medical, we support patients in learning about how terpenes like nerolidol may fit into their treatment plans.
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